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Hepatitis C Virus Research

Recent research interests

bulletWe are studying HCV isolated from patients and cultured by our our collaborators at CIMM.  We are analyzing the virus in patients and comparing it to the cultured virus in order to determine how culturing the virus in different cell types affects it.  We are also studying the replication of the HCV.

Recent publications

bullet Human cell types important for Hepatitis C Virus replication in vivo and in vitro.  Old assertions and current evidence.
Dennis Revie, S Zaki Salahuddin.
Virology Journal 8:346 (July 11, 2011).

bullet Analysis of the 5'UTR of HCV genotype 3 grown in vitro in human B cells, T cells, and macrophages. 
Dennis Revie, Michael O Alberti*, John G Prichard, Ann S Kelley, S Zaki Salahuddin. 
Virology Journal 7:155 (July 13, 2010).

bullet The simultaneous presence and expression of human hepatitis C virus (HCV), human herpesvirus-6 (HHV-6), and human immunodeficiency virus-1 (HIV-1) in a single human T-cell

S Zaki Salahuddin, Katherine A Snyder*, Andre Godwin*, Renu Grewal, John G Prichard, Ann S Kelley, Dennis Revie
 Virology Journal 2007, 4:106 (24 September 2007)

 

bullet Discovery of significant variants containing large deletions in the 5'UTR of human hepatitis C virus (HCV)
 Dennis Revie, Michael O Alberti*, Ravi S Braich, David Bayles, John G Prichard, S Zaki Salahuddin
Virology Journal 2006, 3:82 (29 September 2006)
 
bullet Analysis of in vitro replicated human hepatitis C virus (HCV) for the determination of genotypes and quasispecies
 Dennis Revie, Michael O Alberti*, Ravi S Braich, Nickolas Chelyapov, David Bayles, John G Prichard, S Zaki Salahuddin
Virology Journal 2006, 3:81 (29 September 2006)
 
bullet

Transmission of human hepatitis C virus from patients in secondary cells for long term culture
 Dennis Revie, Ravi S Braich, David Bayles, Nickolas Chelyapov, Rafat Khan, Cheryl Geer, Richard Reisman, Ann S Kelley, John G Prichard, S. Zaki Salahuddin
 Virology Journal 2005, 2:37 (19 April 2005)
 

* = Undergraduate CLU student

bulletComing soon: more HCV papers

Lab protocols

bulletSee Protocols

Collaborators

bulletZaki Salahuddin, CIMM

Hepatitis C virus links

bullet Center for Disease Control (CDC) information on HCV
bullet NIH statement on the management of HCV
bullet World Health Organization (WHO) on HCV

 

Last updated on: January 25, 2012

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Copyright 2013 by Dr. Dennis Revie, all rights reserved.
For problems or questions regarding this web contact: revie@clunet.edu.